What not to do before a PSA blood test?

What to Avoid Before a PSA Blood Test

If you're scheduled for a PSA (prostate-specific antigen) blood test, what you do in the two days leading up to it can influence the results. While this test helps screen for prostate issues, including inflammation or cancer, certain activities can temporarily raise PSA levels—even if nothing is wrong.

First, hold off on anal sex. The physical stimulation can irritate the prostate gland and cause PSA levels to spike. Similarly, ejaculation—whether through sex or masturbation—can also elevate your levels. Since PSA is produced in the prostate and found in semen, releasing semen might prompt a temporary increase in the bloodstream.

Another key factor is strenuous physical activity. Intense workouts—especially those involving heavy lifting or cycling—can put pressure on the pelvic area and affect the prostate. So, while staying active is generally good for prostate health, it’s best to skip anything that leaves you breathless or sore right before the test.

Other things to keep in mind: avoid prostate exams (like a digital rectal exam) or procedures such as cystoscopy shortly before the test, and let your doctor know if you’ve had a recent urinary infection. Even riding a bike the day before could skew results.

The goal is to get the most accurate reading possible. Temporary spikes in PSA don’t mean there’s a problem—but they can lead to unnecessary worry or further testing. By following these simple precautions, you help ensure the results reflect your true prostate health.

Talk to your doctor if you're unsure, but when in doubt: take it easy for two days before the test. No sex, no intense workouts, no risks. Your results will thank you.