Desfuroylceftiofur is the principal active metabolite.

Desloratadine is the primary active metabolite of loratadine.

Desloratadine is the primary active metabolite of loratadine.

After administration, ceftiofur is quickly metabolised to desfuroylceftiofur, the principal active metabolite.

The main metabolite is the para hydroxy derivative which is also pharmacologically active.

It is rapidly and extensively hydrolysed by non specific plasma esterases to the 5 hydroxymethyl derivative, its primary active metabolite, which is the main active pharmacological principle of fesoterodine.

The primary active metabolite comprises 23 to 37 of the total exposure.

Extending these schemes will make a significant contribution to reinforcing social cohesion and creating a more inclusive job market for target groups within Belgium.

Berly Thomas, a journalist and an active blogger elaborates on all points discussed by the mainstream media.

Aescin is the main active compound in horse chestnut, and is responsible for most of its medicinal properties.

1 Aminoindan is an active major metabolite and it is not a MAO B inhibitor.

The major active metabolite was not evaluated for genetic toxicity potential.

The N desmethylated derivative of ivabradine has been identified as the main active metabolite in humans.

Tests on the major active metabolite of riluzole gave positive results in two in vitro tests.

The major metabolite desloratadine (DL) is pharmacologically active and responsible for a large part of the clinical effect.

The major active metabolite is the N desmethylated derivative (S 18982) with an exposure about 40 of that of the parent compound.

Both losartan and its principal active metabolite have a far greater affinity for the AT1 receptor than for the AT2 receptor.

Both Losartan and its principal active metabolite have a far greater affinity for the AT1 receptor than for the AT2 receptor.

The primary metabolite resulting from the cleavage of Arg3 Pro4 bond of the N terminal sequence by thrombin is not active because of the loss of affinity to the catalytic active site of thrombin.

In vitro and in vivo studies indicate that venlafaxine is biotransformed to its major active metabolite, ODV, by CYP2D6.

The massive corporate data store that Google has accumulated through all of our individual searches has become its most valuable asset.

Steady state concentrations of sunitinib and its primary active metabolite are achieved within 10 to 14 days.

Biotransformation Sunitinib is metabolized primarily by CYP3A4, the cytochrome P450 enzyme, which produces its primary active metabolite, which is then further metabolized by CYP3A4.

Unfortunately, the report fails to name and shame big business in the fishing and fish processing sector as the main cause of these problems.

The primary metabolic pathway for riluzole is initial oxidation by cytochrome P450 1A2 producing N hydroxy riluzole (RPR112512), the major active metabolite of riluzole.

The main American manufacturer of that active ingredient decided a few years ago to relocate to China because it's the world's biggest supplier of pigs.

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active consumer,

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With repeated daily administration, sunitinib accumulates 3 to 4 fold and its primary active metabolite accumulates 7 to 10 fold.

No significant changes in the pharmacokinetics of sunitinib or the primary, active metabolite are observed with repeated daily administration or with repeated cycles in the dosing regimens tested.

No significant changes in the pharmacokinetics of sunitinib or the primary, active metabolite are observed with repeated daily administration or with repeated cycles in the dosing regimens tested.

Namibian President Nujoma's active support for President Mugabe and the deafening silence from President Mbeki, the great initiator of the NEPAD programme, which is all about rulers' responsibilities towards the ruled, is worrying.